The Eiga team's work is centered around three principal areas.
- Magnetic Nano Particle Separator
- Cancer diagnostics
- Autoimmune response of cancer
1. Magnetic Nano Particle Separator
Magnetic Separator device is protected by patent
The invention relates to the field of ecology, biotechnology, molecular biology, biological chemistry, immunology, in particular to detection of components with the help of specific interactions between the latter and a microcarrier comprising a receptor immobilized thereon for defining said components. Increasing the reliability of simultaneous detection of a number of components in a mixture, making the analysis cheaper and less time-consuming, extending the range of markers used as well as providing the possibility of visual registration of the contents of a number of components in a mixture is achieved by a method and a device for simultaneous detection of a number of components in a mixture, said method comprising a step of reacting of the components under analysis with the specific receptors immobilized on the surfaces of microcarriers of various forms. As a result of formation of specific complexes a mobility of microcarriers under the influence of a physical field is changed. Due to the change of mobility of microcarriers under the influence of a physical field a separation into a fraction of non-reacted microcarriers with unchanged mobility, and a fraction or fractions of microcarriers with changed mobility. Since each type of a specific receptor is bound to its marked microcarrier the analysis of just a marker characteristic of microcarriers with changed mobility under the influence of a physical field will reveal the availability of the component which has reacted with this microcarrier in the mixture under analysis. Under a physical field as in the case described a gravitation field, an electric field or a magnetic field as well as combinations of .the above is understood. A more efficient reacting of the mixture components with a minimum amount of microcarriers , provision of an efficient and operation-saving separation of microcarriers is achieved in a convenient for sterilization separating chamber where the process of retaining the microcarriers on the walls of a separating chamber and removing them into the collector is actually continuous.
2005 discovery made
Method and device for simultaneous detection of multiple components in a mixture.
Document Type and Number
Europea Patent EP1365241
Code A2
Treatment method and diagnostics for early cancer are protected by patent application.
Protein complexes for prevention and treatment of diseases with angiogenesis disorders.
Doucment Type and Number
Wipo Patent WO/2008/006187
Code A2
2.Cancer diagnostics
3. Autoimmune response of cancer
3. Autoimmune response of cancer
The invention relates to the medical field, and in particular, to protein complexes and application thereof for the correction of autoimmune processes in human or animal bodies and also to a research of biochemical mechanisms of diseases with angiogenesis disorders. The protein complexes claimed comprise an antigen and an effector portion attached thereto wherein said antigen presents an angiogenic factor. An angiogenic factors of a protein complexes could be both pro-angiogenic and anti-angiogenic. An effector portion can either show of immunomodulating activity, or provide the specific influence on a target immunocompetent cells Moreover, it can be made in the form of a polymer carrier for depleting of target autoantibodies and immunocompetent cells. There are also claimed the use of new protein complexes, the new methods of treatment of diseases with angiogenesis disorders and a new method and a new test-system for monitoring of angiogenesis disorders for use in the above methods of treatment. The inventors are emphasizing the role of autoimmune mechanism in origin of malignant growth and the importance of subject of the invention for early cancer diagnostics, prevention and treatment
Started clinical trials Feb 2007
